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Application of 'next-generation' sequencing technologies to microbial genetics

TitleApplication of 'next-generation' sequencing technologies to microbial genetics
Publication TypeJournal Article
Year of Publication2009
AuthorsMacLean, D, Jones JDG, Studholme DJ
JournalNature Reviews Microbiology
Volume7
Pagination287-296
Date PublishedApr
ISBN Number1740-1526
Accession NumberISI:000264179900012
Abstract

New sequencing methods generate data that can allow the assembly of microbial genome sequences in days. With such revolutionary advances in technology come new challenges in methodologies and informatics. In this article, we review the capabilities of high-throughput sequencing technologies and discuss the many options for getting useful information from the data.

URL<Go to ISI>://000264179900012